Activity record

PGDB_A064642

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 219.2 nM

TargetGSPT1
Cell lineCAL-51
Time6 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS001139
PatentCN119264113A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000671
Compound IDPGDB_C000671
Compound化合物 1;化合物 1;化合物1
Source record IDPGDB_C000671
InChIKeyKDRRVRVTBUWVFT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001139
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time6 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineCAL-51

Source evidence

Patent IDCN119264113A
Compound location

化合物 1;化合物 1;化合物1

化合物 1;化合物 1;化合物1 enlarged structure化合物 1;化合物 1;化合物1 location on patent page 3
Activity table
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