Activity record

PGDB_A065544

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

IC50 = 0.073 uM

TargetCDK2
Cell lineHEK293
Time6 h
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001302
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007989
Compound IDPGDB_C007989
Compound84;84
Source record IDPGDB_C007989
InChIKeyDEVHFIFWWGLUJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001302
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

84;84

84;84 enlarged structure84;84 location on patent page 25
Activity table
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