Activity record

PGDB_A065558

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 52 nM

TargetIKZF2
Time20 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000215
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010125
Compound IDPGDB_C010125
CompoundEXAMPLE 1
Source record IDPGDB_C010125
InChIKeyZMLKQUYYZBYSNQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000215
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time20 h
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 81
Activity table
Page 106 · table single