Activity record

PGDB_A065734

Assay: viabilityTarget: CCNKQC: ambiguous
Activity overview

GI50 > 3000 nM

TargetCCNK
Cell lineTHP-1
Time144 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS002373
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011976
Compound IDPGDB_C011976
Compound110
Source record IDPGDB_C011976
InChIKeyKJNQRMUUYDRQII-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002373
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time144 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
Cell lineTHP-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

110

110 enlarged structure110 location on patent page 145
Activity table
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