Activity record

PGDB_A067782

Assay: biochemicalTarget: KRASQC: ambiguous
Activity overview

IC50 = 1-10 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS002054
PatentWO2025214350A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011612
Compound IDPGDB_C011612
CompoundExample 31
Source record IDPGDB_C011612
InChIKeyPPUJHEMTHBFWPK-WWKBNDPPSA-N

Assay context

Assay IDPGDB_AS002054
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1 | SOS1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 31

Example 31 enlarged structureExample 31 location on patent page 59
Activity table
Page 221 · table start
Page 222 · table end