Activity record

PGDB_A069164

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

Dmax = 78 %

TargetIKZF4
ConcentrationConcentration context: titrated doses
Time13 d
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS000221
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010131
Compound IDPGDB_C010131
Compound2
Source record IDPGDB_C010131
InChIKeySTBPHXSTASSXPE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000221
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time13 d
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

2

2 enlarged structure2 location on patent page 78
Activity table
Page 92 · table single