Activity record

PGDB_A069184

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 99.92 %

TargetGSPT1
Cell lineHEK293T
Time18 h
Assay / Readoutluminescence / % Degradation
Assay IDPGDB_AS000448
PatentWO2023001028A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001869
Compound IDPGDB_C001869
CompoundWX006;WX006
Source record IDPGDB_C001869
InChIKeyWVZGPOLTAMASFO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000448
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyluminescence
Treatment time18 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDWO2023001028A1
Compound location

WX006;WX006

WX006;WX006 enlarged structureWX006;WX006 location on patent page 25
Activity table
Page 43 · table single