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Compound
PGDB_C001869
4 activity records1 related patents
2D structure
Cc1c(Cl)cc(NC(=O)NCc2ccc3c(C4CCC(=O)NC4=O)coc3c2)cc1OCCN1CCOCC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 4.7 | nM | - | — | GSPT1 | - | MDA-MB-231 | WO2023001028A1 | PGDB_A039660 | PGDB_C001869 | PGDB_AS001716 | View |
| % Degradation | - | = | 99.92 | % | - | 18 h | GSPT1 | - | HEK293T | WO2023001028A1 | PGDB_A069184 | PGDB_C001869 | PGDB_AS000448 | View |
| DC50 | - | = | 1.94 | nM | - | — | GSPT1 | - | HEK293T | WO2023001028A1 | PGDB_A074210 | PGDB_C001869 | PGDB_AS002023 | View |
| % Inhibition | - | = | 80.3 | % | - | 3 d | GSPT1 | - | MDA-MB-231 | WO2023001028A1 | PGDB_A076912 | PGDB_C001869 | PGDB_AS001682 | View |