Activity record

PGDB_A069261

Assay: biochemicalTarget: CTNNB1QC: ambiguous
Activity overview

EC50 = 1-10 uM

TargetCTNNB1
E3 ligaseBTRC | FBXW11
Time1 h
Assay / ReadoutEC50 / biochemical
Assay IDPGDB_AS000640
PatentWO2025179005A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C021141
Compound IDPGDB_C021141
Compound233
Source record IDPGDB_C021141
InChIKeySGPKIIAMMNVUSG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000640
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
Treatment time1 h
TargetBTRC | FBXW11 | SKP1
E3BTRC | FBXW11 | SKP1

Source evidence

Patent IDWO2025179005A1
Compound location

233

233 enlarged structure233 location on patent page 542
Activity table
Page 700 · table start
Page 701 · table middle
Page 702 · table end