Activity record

PGDB_A069782

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

DC50 = 193 nM

TargetIKZF4
Time20 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS000023
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010126
Compound IDPGDB_C010126
Compound2
Source record IDPGDB_C010126
InChIKeyKLWWIJBBBDWGRY-VNHLFDKOSA-N

Assay context

Assay IDPGDB_AS000023
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time20 h
Detection targetprotein_degradation
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

2

2 enlarged structure2 location on patent page 85
Activity table
Page 106 · table single