Activity record

PGDB_A070132

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1.67 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000095
PatentWO2024032689A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002517
Compound IDPGDB_C002517
CompoundGT-05599
Source record IDPGDB_C002517
InChIKeyDZKMGSCISBORDP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000095
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1
Compound location

GT-05599

GT-05599 enlarged structureGT-05599 location on patent page 82
Activity table
Page 248 · table start
Page 249 · table middle
Page 250 · table end