Activity record

PGDB_A070195

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 40.9 nM

TargetCDK12
Cell lineMDA-MB-468
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000556
PatentCN121108130A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007326
Compound IDPGDB_C007326
Compound实施例2;实施例2
Source record IDPGDB_C007326
InChIKeyPCGMHUPHPDJBLV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000556
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified
Cell lineMDA-MB-468

Source evidence

Patent IDCN121108130A
Compound location

实施例2;实施例2

实施例2;实施例2 enlarged structure实施例2;实施例2 location on patent page 21
Activity table
Page 36 · table single