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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A070219

Assay: % DegradationTarget: GSPT1QC: ambiguous

Activity overview

Dmax = 117 %

TargetGSPT1

Cell lineNB4

Concentration5 mM

Time4 h

Assay / Readoutluminescence / Dmax

Assay IDPGDB_AS000646

PatentWO2025146129A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C003355

Compound23;化合物 23

Source record IDPGDB_C003355

InChIKeyQUBTXUZJNGIQKF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000646

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

Technologyluminescence

Concentration5 mM

Treatment time4 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell lineNB4

Source evidence

Patent IDWO2025146129A1

Compound location

23;化合物 23

23;化合物 23 enlarged structure

23;化合物 23 location on patent page 15

Activity table

Page 56 · table start

Page 57 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU