Activity record

PGDB_A070251

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 0.35 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS001469
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020452
Compound IDPGDB_C020452
Compound279
Source record IDPGDB_C016300
InChIKeyJLMXAURJLLEANJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001469
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

279

279 enlarged structure279 location on patent page 88
Activity table
Page 416 · table single