Activity record

PGDB_A070272

Assay: % DegradationQC: standardized
Activity overview

Emax > 60 %

Cell line293T.114
TimeDC50 > 10000 nM
Assay / Readoutluminescence / Emax
Assay IDPGDB_AS000364
PatentWO2022081927A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C016646
Compound IDPGDB_C016646
Compound{4498}
Source record IDPGDB_C026794
InChIKeyGKQJJZFZGKFFSE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000364
Assay family% Degradation
Assay systemcell_based
ReadoutEmax
Technologyluminescence
Treatment timeDC50 > 10000 nM
TargetGSPT1
E3CRBN
Cell line293T.114
OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1
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