Assay

PGDB_AS000364

System: cell_basedTarget: GSPT1Cell line: 293T.114
Assay context summary

Assay context

4 activity records
Assay family% Degradation
Systemcell_based
ReadoutEmax
TargetGSPT1
E3CRBN
Cell line293T.114
OrganismHomo sapiens
Technologyluminescence
Activity compounds and values

Activity records

4 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C016648
Emax->60%-DC50 > 10000 nM--293T.114WO2022081927A1PGDB_A010271PGDB_C016648PGDB_AS000364View
2D structure for PGDB_C016646
Emax->60%-DC50 > 10000 nM--293T.114WO2022081927A1PGDB_A070272PGDB_C016646PGDB_AS000364View
2D structure for PGDB_C016637
Emax->60%-DC50 > 10000 nM--293T.114WO2022081927A1PGDB_A072255PGDB_C016637PGDB_AS000364View
2D structure for PGDB_C016644
Emax->60%-DC50 > 10000 nM--293T.114WO2022081927A1PGDB_A075665PGDB_C016644PGDB_AS000364View
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