Activity record

PGDB_A070688

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

EC50 = 2 nM

TargetIKZF2
Cell lineJurkat
Timeovernight
Assay / Readoutflow_cytometry / EC50
Assay IDPGDB_AS002391
PatentJP2026020265A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008427
Compound IDPGDB_C008427
CompoundExample 46;Example 46
Source record IDPGDB_C008427
InChIKeyQDZFZUGIHOOPGR-HWWMDGIVSA-N

Assay context

Assay IDPGDB_AS002391
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyflow_cytometry
Treatment timeovernight
TargetIKZF2
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDJP2026020265A
Compound location

Example 46;Example 46

Example 46;Example 46 enlarged structureExample 46;Example 46 location on patent page 323
Activity table
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