Activity record

PGDB_A070691

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.51 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000368
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007993
Compound IDPGDB_C007993
Compound88;88
Source record IDPGDB_C007993
InChIKeyLOXVEYVHUFHZSO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000368
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

88;88

88;88 enlarged structure88;88 location on patent page 25
Activity table
Page 527 · table start
Page 528 · table end