Activity record

PGDB_A070963

Assay: viabilityTarget: BRAFQC: standardized
Activity overview

GI50 = 55 nM

TargetBRAF
Cell lineA375-NRASQ61K
Time96 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS001149
PatentAU2022290851A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005652
Compound IDPGDB_C005652
Compound157;Example 157
Source record IDPGDB_C005652
InChIKeyOCDRMYDQTIPVOI-HHHXNRCGSA-N

Assay context

Assay IDPGDB_AS001149
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time96 h
TargetBRAF
E3Not specified
Cell lineA375-NRASQ61K

Source evidence

Patent IDAU2022290851A1
Compound location

157;Example 157

157;Example 157 enlarged structure157;Example 157 location on patent page 5
Activity table
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