Activity record

PGDB_A071144

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 25 nM

TargetIKZF2
Time13 d
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001515
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007382
Compound IDPGDB_C007382
CompoundComparative Compound B
Source record IDPGDB_C007382
InChIKeyUZLMRMVUVTXJJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001515
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time13 d
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 86
Activity table
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