Activity record

PGDB_A071622

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

DC50 = 76 nM

TargetNEK7
Cell lineCAL-51
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001365
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020451
Compound IDPGDB_C020451
Compound278
Source record IDPGDB_C020451
InChIKeySIIPPJNYNGWKGD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001365
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2025024521A1
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