Activity record

PGDB_A071643

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

IC50 = 0.081 uM

TargetCDK2
Cell lineHEK293
Time6 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000366
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008038
Compound IDPGDB_C008038
Compound57;57;57
Source record IDPGDB_C008038
InChIKeyXFPSSQZPVBUIPZ-OECOBVRJSA-N

Assay context

Assay IDPGDB_AS000366
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 h
Detection targetprotein_degradation
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

57;57;57

57;57;57 enlarged structure57;57;57 location on patent page 39
Activity table
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