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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A072577

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

Emax > 95 %

TargetGSPT1

Cell line293T.114

Concentration10 uM

TimeDC50 > 10000 nM

Assay / Readoutluminescence / Emax

Assay IDPGDB_AS000916

PatentAU2021361043A9

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C019160

Compound105;105

Source record IDPGDB_C019160

InChIKeyAZDVEZVPGIZNTJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000916

Assay family% Degradation

Assay systemcell_based

ReadoutEmax

Technologyluminescence

Concentration10 uM

Treatment timeDC50 > 10000 nM

TargetGSPT1

E3Not specified

Cell line293T.114

OrganismHomo sapiens

Source evidence

Patent IDAU2021361043A9

Compound location

105;105

105;105 enlarged structure

105;105 location on patent page 247

Activity table

Page 287 · table start

Page 288 · table middle

Page 289 · table middle

Page 290 · table middle

Page 291 · table middle

Page 292 · table middle

Page 293 · table middle

Page 294 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU