Activity record

PGDB_A072721

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 7.9 nM

TargetGSPT1
Cell lineHL-60
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002047
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005305
Compound IDPGDB_C005305
Compound4-152;4-152;4-152
Source record IDPGDB_C005305
InChIKeyFGHCZPKOLZERDH-IAXKEJLGSA-N

Assay context

Assay IDPGDB_AS002047
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023078410A1
Compound location

4-152;4-152;4-152

4-152;4-152;4-152 enlarged structure4-152;4-152;4-152 location on patent page 7
Activity table
Page 92 · table start
Page 93 · table end