Activity record

PGDB_A072734

Assay: selectivityTarget: KCNH2QC: standardized
Activity overview

inhibition = 12.86 %

TargetKCNH2
Cell lineHEK293
Concentration3 uM
Time3 min
Assay / Readout% Inhibition / selectivity
Assay IDPGDB_AS000812
PatentWO2023274246A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002384
Compound IDPGDB_C002384
Compound实施例 71
Source record IDPGDB_C002384
InChIKeyJQRJUPRWQDRSHQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000812
Assay familyselectivity
Assay systemcell_based
Readout% Inhibition
Concentration3 uM
Treatment time3 min
Detection targetcell_inhibition
TargetKCNH2
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2023274246A1
Compound location

实施例 71

实施例 71 enlarged structure实施例 71 location on patent page 37
Activity table
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