PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

13 activity records

Assay familyselectivity

Systemcell_based

Readout% Inhibition

TargetKCNH2

E3Not specified

Cell lineHEK293

OrganismHomo sapiens

Detection targetcell_inhibition

Activity compounds and values

13 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Inhibition	-	=	2.25	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A023586	PGDB_C002385	PGDB_AS000812	View
% Inhibition	-	=	-0.68	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A028928	PGDB_C002370	PGDB_AS000812	View
% Inhibition	-	=	-3	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A039123	PGDB_C002381	PGDB_AS000812	View
% Inhibition	-	=	5.39	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A041314	PGDB_C002371	PGDB_AS000812	View
% Inhibition	-	=	-5.31	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A042651	PGDB_C002393	PGDB_AS000812	View
% Inhibition	-	=	-0.61	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A042668	PGDB_C002344	PGDB_AS000812	View
% Inhibition	-	=	4.65	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A048748	PGDB_C002372	PGDB_AS000812	View
% Inhibition	-	=	-0.53	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A050625	PGDB_C002396	PGDB_AS000812	View
% Inhibition	-	=	-3.22	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A063865	PGDB_C002326	PGDB_AS000812	View
% Inhibition	-	=	-2.36	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A067729	PGDB_C002340	PGDB_AS000812	View
% Inhibition	-	=	1.85	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A070222	PGDB_C002351	PGDB_AS000812	View
% Inhibition	-	=	12.86	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A072734	PGDB_C002384	PGDB_AS000812	View
% Inhibition	-	=	3.91	%	3 uM	3 min	KCNH2	-	HEK293	WO2023274246A1	PGDB_A073505	PGDB_C002395	PGDB_AS000812	View

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