Activity record

PGDB_A072996

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 52 %

TargetIKZF1
ConcentrationConcentration context: titrated doses
Time24 h
Assay / Readoutflow_cytometry / % Degradation
Assay IDPGDB_AS000316
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010126
Compound IDPGDB_C010126
Compound2
Source record IDPGDB_C010126
InChIKeyKLWWIJBBBDWGRY-VNHLFDKOSA-N

Assay context

Assay IDPGDB_AS000316
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time24 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

2

2 enlarged structure2 location on patent page 85
Activity table
Page 110 · table single