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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A073172

Assay: % DegradationTarget: GSPT1QC: ambiguous

Activity overview

degradation < 20 %

TargetGSPT1

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS001137

PatentWO2024245444A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C020054

CompoundGT-06974

Source record IDPGDB_C020054

InChIKeyYZMHZWRAIUSTMK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001137

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1

Compound location

GT-06974

GT-06974 enlarged structure

GT-06974 location on patent page 69

Activity table

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU