Activity record

PGDB_A073291

Assay: % DegradationQC: ambiguous
Activity overview

DC50 = 6 nM

Cell lineMM.1S
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001567
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001783
Compound IDPGDB_C001783
Compound29
Source record IDPGDB_C001783
InChIKeySRLWKYYCZPYURO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001567
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetIKZF1 | IKZF3
E3Not specified
Cell lineMM.1S

Source evidence

Patent IDWO2022219412A1
Compound location

29

29 enlarged structure29 location on patent page 111
Activity table
Page 171 · table single