Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A073376

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

degradation = 45 %

TargetGSPT1

Cell lineHL-60

Concentration1 uM

Time2 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS001173

PatentWO2024073871A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C002872

Compound23;23;23;23

Source record IDPGDB_C002872

InChIKeyUAEXGWFMZNFPAE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001173

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration1 uM

Treatment time2 h

Detection targetprotein_degradation

TargetGSPT1

E3Not specified

Cell lineHL-60

Source evidence

Patent IDWO2024073871A1

Compound location

23;23;23;23

23;23;23;23 enlarged structure

23;23;23;23 location on patent page 31

Activity table

Page 93 · table start

Page 94 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU