Activity record

PGDB_A073753

Assay: viabilityQC: standardized
Activity overview

IC50 = 4.2 nM

Cell lineNCI-H1155
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001656
PatentWO2024125437A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005363
Compound IDPGDB_C005363
Compound实施例 4
Source record IDPGDB_C005363
InChIKeyJNPQHBXSTIPACU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001656
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection target% Cell viability
E3Not specified
Cell lineNCI-H1155
OrganismHomo sapiens

Source evidence

Patent IDWO2024125437A1
Compound location

实施例 4

实施例 4 enlarged structure实施例 4 location on patent page 17
Activity table
Page 36 · table single