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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A074182

Assay: % DegradationTarget: GSPT1QC: standardized

Activity overview

Dmax = 58.5 %

TargetGSPT1

E3 ligaseCRBN

Cell lineHT-1080

Concentration10 uM

Time20 h

Assay / ReadoutDmax / % Degradation

Assay IDPGDB_AS000618

PatentWO2022257897A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C001802

Compound18

Source record IDPGDB_C001802

InChIKeyJQTLNXOXLYPEKD-IJHRGXPZSA-N

Assay context

Assay IDPGDB_AS000618

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

Concentration10 uM

Treatment time20 h

TargetGSPT1

E3CRBN

Cell lineHT-1080

OrganismHomo sapiens

Source evidence

Patent IDWO2022257897A1

Compound location

18

18 enlarged structure

18 location on patent page 80

Activity table

Page 134 · table start

Page 135 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU