Assay

PGDB_AS000618

System: cell_basedTarget: GSPT1Cell line: HT-1080
Assay context summary

Assay context

90 activity records
Assay family% Degradation
Systemcell_based
ReadoutDmax
TargetGSPT1
E3CRBN
Cell lineHT-1080
OrganismHomo sapiens
Activity compounds and values

Activity records

90 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001853
Dmax-=19.1%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A007839PGDB_C001853PGDB_AS000618View
2D structure for PGDB_C001801
Dmax-=49.3%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A008752PGDB_C001801PGDB_AS000618View
2D structure for PGDB_C001816
Dmax-=47.9%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A009419PGDB_C001816PGDB_AS000618View
2D structure for PGDB_C001804
Dmax-=42%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A010132PGDB_C001804PGDB_AS000618View
2D structure for PGDB_C001849
Dmax-=31.7%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A011083PGDB_C001849PGDB_AS000618View
2D structure for PGDB_C001806
Dmax-=30.6%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A011475PGDB_C001806PGDB_AS000618View
2D structure for PGDB_C001814
Dmax-=42.7%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A011560PGDB_C001814PGDB_AS000618View
2D structure for PGDB_C001826
Dmax-=70.8%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A011967PGDB_C001826PGDB_AS000618View
2D structure for PGDB_C001863
Dmax-=14.9%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A012267PGDB_C001863PGDB_AS000618View
2D structure for PGDB_C001844
Dmax-=29%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A013401PGDB_C001844PGDB_AS000618View
2D structure for PGDB_C001784
Dmax-=28.6%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A013789PGDB_C001784PGDB_AS000618View
2D structure for PGDB_C001834
Dmax-=36.2%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A014748PGDB_C001834PGDB_AS000618View
2D structure for PGDB_C000058
Dmax-=92.5%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A015056PGDB_C000058PGDB_AS000618View
2D structure for PGDB_C001805
Dmax-=32.5%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A015766PGDB_C001805PGDB_AS000618View
2D structure for PGDB_C001795
Dmax-=23.4%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A016720PGDB_C001795PGDB_AS000618View
2D structure for PGDB_C001815
Dmax-=24.2%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A017558PGDB_C001815PGDB_AS000618View
2D structure for PGDB_C001824
Dmax-=30.7%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A018416PGDB_C001824PGDB_AS000618View
2D structure for PGDB_C001818
Dmax-=16.5%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A018471PGDB_C001818PGDB_AS000618View
2D structure for PGDB_C001852
Dmax-=58%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A020280PGDB_C001852PGDB_AS000618View
2D structure for PGDB_C001860
Dmax-=16.2%10 uM20 hGSPT1CRBNHT-1080WO2022257897A1PGDB_A020432PGDB_C001860PGDB_AS000618View
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