Activity record

PGDB_A074210

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 1.94 nM

TargetGSPT1
Cell lineHEK293T
Time18 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS002023
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001869
Compound IDPGDB_C001869
CompoundWX006;WX006
Source record IDPGDB_C001869
InChIKeyWVZGPOLTAMASFO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002023
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time18 h
TargetGSPT1
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2023001028A1
Compound location

WX006;WX006

WX006;WX006 enlarged structureWX006;WX006 location on patent page 25
Activity table
Page 43 · table single