Activity record

PGDB_A074243

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

degradation = 81.61 %

TargetGSPT1
Cell lineNCI-H1155
ConcentrationConcentration context: 10 nM
Time6 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS000061
PatentWO2024125437A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001479
Compound IDPGDB_C001479
Compound化合物 A
Source record IDPGDB_C001479
InChIKeyHNTGMIGBGVFOBT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000061
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
ConcentrationConcentration context: 10 nM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024125437A1
Compound location

化合物 A

化合物 A enlarged structure化合物 A location on patent page 35
Activity table
Page 39 · table single