Activity record

PGDB_A074361

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 3.88 nM

TargetGSPT1
Cell lineSK-BR-3
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001340
PatentWO2025252247A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005471
Compound IDPGDB_C005471
Compound化合物 19;化合物19;实施例 19;实施例 19
Source record IDPGDB_C005471
InChIKeyCYSHQAMBOILYQL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001340
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineSK-BR-3

Source evidence

Patent IDWO2025252247A1
Compound location

化合物 19;化合物19;实施例 19;实施例 19

化合物 19;化合物19;实施例 19;实施例 19 enlarged structure化合物 19;化合物19;实施例 19;实施例 19 location on patent page 82
Activity table
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