Activity record

PGDB_A074738

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 75.89 nM

TargetCDK12
Cell lineMDA-MB-231
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001069
PatentCN121108130A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007330
Compound IDPGDB_C007330
Compound实施例7
Source record IDPGDB_C007330
InChIKeyULMYAPUXTIWYPS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001069
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified
Cell lineMDA-MB-231
OrganismHomo sapiens

Source evidence

Patent IDCN121108130A
Compound location

实施例7

实施例7 enlarged structure实施例7 location on patent page 24
Activity table
Page 36 · table single