Activity record

PGDB_A075027

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.39 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000095
PatentWO2024032689A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002509
Compound IDPGDB_C002509
CompoundGT-05640
Source record IDPGDB_C002509
InChIKeyRHHGYLJKFDNPFG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000095
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1
Compound location

GT-05640

GT-05640 enlarged structureGT-05640 location on patent page 58
Activity table
Page 248 · table start
Page 249 · table middle
Page 250 · table end