Activity record

PGDB_A075089

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1-1.5 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS002101
PatentWO2024245444A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019943
Compound IDPGDB_C019943
CompoundGT-05073
Source record IDPGDB_C019943
InChIKeyYNMRDLKSUYFXDO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002101
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1
Compound location

GT-05073

GT-05073 enlarged structureGT-05073 location on patent page 61
Activity table
Page 260 · table single