Activity record

PGDB_A075133

Assay: biochemicalTarget: KRASQC: ambiguous
Activity overview

IC50 = 10-100 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS002054
PatentWO2025214350A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011618
Compound IDPGDB_C011618
CompoundExample 67;Example 67
Source record IDPGDB_C011618
InChIKeyLSHXOXDGDHXBKQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002054
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1 | SOS1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 67;Example 67

Example 67;Example 67 enlarged structureExample 67;Example 67 location on patent page 61
Activity table
Page 221 · table start
Page 222 · table end