Activity record

PGDB_A075951

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 100-1000 nM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000488
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020439
Compound IDPGDB_C020439
Compound266.0
Source record IDPGDB_C016569
InChIKeyLMSNQEBHCGVTKQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000488
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

266.0

266.0 enlarged structure266.0 location on patent page 87
Activity table
Page 416 · table start
Page 417 · table middle
Page 418 · table end