Activity record

PGDB_A076222

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

Dmax = 89.9 %

TargetIKZF1
Cell lineHT-1080
ConcentrationConcentration context: HiBiT IKZF1:_D max (%)
Time20 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001371
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007552
Compound IDPGDB_C007552
Compound化合物 9-A
Source record IDPGDB_C007552
InChIKeyHULAZOQCQMEDII-WJOKGBTCSA-N

Assay context

Assay IDPGDB_AS001371
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration context: HiBiT IKZF1:_D max (%)
Treatment time20 h
Detection targetprotein_degradation
TargetIKZF1
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物 9-A

化合物 9-A enlarged structure化合物 9-A location on patent page 108
Activity table
Page 121 · table single