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Compound
PGDB_C007552
8 activity records1 related patents
2D structure
N#Cc1ccc(N2CCN(Cc3ccc(Cc4ccc5c6c(cc(F)cc46)C(=O)N5[C@@H]4CCC(=O)NC4=O)cc3)CC2)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 93.1 | % | - | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A012487 | PGDB_C007552 | PGDB_AS000825 | View |
| DC50 | - | = | 0.23 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A014100 | PGDB_C007552 | PGDB_AS001653 | View |
| Dmax | - | = | 57 | % | Concentration context: HiBiT SALL4: D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A024136 | PGDB_C007552 | PGDB_AS001601 | View |
| DC50 | - | = | 0.292 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A027134 | PGDB_C007552 | PGDB_AS000460 | View |
| DC50 | - | = | 0.328 | uM | - | — | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A028206 | PGDB_C007552 | PGDB_AS000384 | View |
| Dmax | - | = | 55.2 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | EP4393915A1 | PGDB_A029432 | PGDB_C007552 | PGDB_AS001879 | View |
| DC50 | - | = | 0.185 | nM | - | — | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A038448 | PGDB_C007552 | PGDB_AS001343 | View |
| Dmax | - | = | 89.9 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | EP4393915A1 | PGDB_A076222 | PGDB_C007552 | PGDB_AS001371 | View |