Activity record

PGDB_A076893

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

IC50 > 833 nM

TargetIKZF1
Time55.7 ± 6.0 | 22.4 ± 3.1
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS000746
PatentCA3173658A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009601
Compound IDPGDB_C009601
CompoundPomalidomide
Source record IDPGDB_C000056
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000746
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time55.7 ± 6.0 | 22.4 ± 3.1
Detection targetprotein_degradation
TargetIKZF1
E3Not specified

Source evidence

Patent IDCA3173658A1
Activity table
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