Activity record

PGDB_A077033

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

degradation > 99 %

TargetIKZF1
Cell lineH929
Concentration10 uM
Time24 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS001613
PatentCN116457344A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000058
Compound IDPGDB_C000058
CompoundCC-885
Source record IDPGDB_C000058
InChIKeyDOEVCIHTTTYVCC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001613
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration10 uM
Treatment time24 h
TargetIKZF1
E3Not specified
Cell lineH929

Source evidence

Patent IDCN116457344A
Compound location

CC-885

CC-885 enlarged structureCC-885 location on patent page 86
Activity table
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