Activity record

PGDB_A077102

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

Dmax = 37 %

TargetIKZF1
Time20 h
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS001941
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007382
Compound IDPGDB_C007382
CompoundComparative Compound B
Source record IDPGDB_C007382
InChIKeyUZLMRMVUVTXJJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001941
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
Treatment time20 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 86
Activity table
Page 89 · table single