Activity record

PGDB_A077294

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

GI50 = 74 nM

TargetGSPT1
Cell lineNCI-H1155
Time72 h
Assay / ReadoutGI50 / viability
Assay IDPGDB_AS000187
PatentWO2024222614A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003211
Compound IDPGDB_C003211
Compound37;37
Source record IDPGDB_C003211
InChIKeyPCWSDHXISPQDKF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000187
Assay familyviability
Assay systemcell_based
ReadoutGI50
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024222614A1
Compound location

37;37

37;37 enlarged structure37;37 location on patent page 16
Activity table
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