Activity record

PGDB_A077359

Assay: % DegradationTarget: IKZF3QC: standardized
Activity overview

Dmax = 80-84 %

TargetIKZF3
ConcentrationConcentration context: titrated doses
Time24 h
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS001615
PatentCN121646585A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008148
Compound IDPGDB_C008148
CompoundEXAMPLE 1
Source record IDPGDB_C008148
InChIKeyWFRMFYGYKOBRFI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001615
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121646585A
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 70
Activity table
Page 80 · table single