Activity record

PGDB_A078203

Assay: viabilityTarget: KRASQC: ambiguous
Activity overview

IC50 = 67.8 nM

TargetKRAS
Cell lineNCI-H727
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000308
PatentWO2026114957A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031939
Compound IDPGDB_C031939
CompoundI-1;I-1;I-1
Source record IDPGDB_C031939
InChIKeyOMHBONXEUVXOQU-BGASMWSGSA-N

Assay context

Assay IDPGDB_AS000308
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineNCI-H727
OrganismHomo sapiens

Source evidence

Patent IDWO2026114957A1
Compound location

I-1;I-1;I-1

I-1;I-1;I-1 enlarged structureI-1;I-1;I-1 location on patent page 145
Activity table
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