Activity record

PGDB_A078287

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 77 nM

TargetCRBN
E3 ligaseCRBN
Cell lineTni(Hi5)insect
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000132
PatentWO2026114958A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031971
Compound IDPGDB_C031971
CompoundI-31
Source record IDPGDB_C031971
InChIKeyNNHLNLJMLNXMID-LJBLSROPSA-N

Assay context

Assay IDPGDB_AS000132
Assay familybinding
Assay systemcell_based
ReadoutIC50
TargetCRBN
E3CRBN
Cell lineTni(Hi5)insect
Organisminsect cells

Source evidence

Patent IDWO2026114958A1
Compound location

I-31

I-31 enlarged structureI-31 location on patent page 265
Activity table
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